None-deuterium-VX-984是VX-984的非氘代形式。VX-984是一种ATP竞争性的DNA-PKcs抑制剂。
CAS:1476071-49-4
分子式:C23H23N7O
分子量:413.48
纯度:98%
存储:Store at -20°C
Background:
None-deuterium-VX-984 is the non-deuterated form of VX-984. VX-984 is an a ATP-competitive DNA-PKcs inhibitor.
[1]. Timme CR, et al. The DNA-PK Inhibitor VX-984 Enhances the Radiosensitivity of Glioblastoma Cells Grown In Vitroand as Orthotopic Xenografts. Mol Cancer Ther. 2018 Jun;17(6):1207-1216.