Flumazenil acid 是 Flumazenil 的一种代谢产物。Flumazenil 是一种 GABAA 受体拮抗剂。
CAS:84378-44-9
分子式:C13H10FN3O3
分子量:275.24
纯度:98%
存储:Store at -20°C
Background:
Flumazenil acid is a metabolite of Flumazenil[1]. Flumazenil is a GABAA receptor antagonist[2].
[1]. Kleingeist B, et al. Isolation and pharmacological characterization of microsomal human liver flumazenil carboxylesterase. J Pharm Pharm Sci. 1998 Jan-Apr;1(1):38-46.
[2]. Mograbi KM, et al. Effects of GABAa receptor antagonists on motor behavior in pharmacological Parkinson’s disease model in mice. Physiol Rep. 2017 Mar;5(6). pii: e13081.