HG6-64-1是有效选择性的B-Raf抑制剂, 来自专利专利WO 2011090738 A2,化合物实例9 (XI-1)。在B-raf V600E转化的Ba/F3细胞中IC50值为0.09 μM。
CAS:1315329-43-1
分子式:C32H34F3N5O2
分子量:577.64
纯度:98%
存储:Store at -20°C
Background:
HG6-64-1 is a potent and selective B-Raf inhibitor extracted from patent WO 2011090738 A2, example 9 (XI-1); has a IC50 of 0.09 μM on B-raf V600E transformed Ba/F3 cells.
B-RafV600E|0.09 μM (IC50, in Ba/F3 cells)
[1]. WO 2011090738 A2