PD-1-IN-17是一种有效的程序性细胞死亡-1(PD-1)抑制剂,详细信息请参考专利文献WO2015033301A1中的化合物12,浓度为100nM时抑制92%脾细胞增殖。
CAS:1673560-66-1
分子式:C13H22N6O7
分子量:374.35
纯度:98%
存储:Store at -20°C
Background:
PD-1-IN-17 is a programmed cell death- 1 (PD-1) inhibitor extracted from patent WO2015033301A1, Compound 12, inhibits 92% splenocyte proliferation at 100 nM[1].
PD-1[1]
[1]. Pottayil Govindan Nair Sasikumar, et al. 1,3,4-oxadiazole and 1,3,4-thiadiazole derivatives as immunomodulators. WO2015033301A1.