DIPQUO 是一种骨标记碱性磷酸酶 (ALP) 激活剂，在 C2C12 细胞中作用的 EC50 值为 6.27 μM。DIPQUO 通过激活 p38 MAPK-β 促进小鼠和人类的成骨细胞分化。
CAS：1269365-82-3
分子式：C20H17N3O
分子量：315.37
纯度：98%
存储：Store at -20°C

Background:

DIPQUO is an activator of the bone marker alkaline phosphatase (ALP), with an EC50 of 6.27 μM in C2C12 cells. DIPQUO promotes mouse and human osteoblast differentiation via activation of p38 MAPK-β[1]. EC50: 6.27 μM (ALP, C2C12 cells)[1]

[1]. Cook B, et al. Discovery of a Small Molecule Promoting Mouse and Human Osteoblast Differentiation via Activation of p38 MAPK-β. Cell Chem Biol. 2019 Mar 29.