CHK-IN-1是一种CHK1和CHK2的抑制剂,具有抗增殖作用。
CAS:1278405-51-8
分子式:C18H19ClFN5OS
分子量:407.89
纯度:98%
存储:Store at -20°C
Background:
CHK-IN-1 is an inhibitor of CHK1 and CHK2, with anti-proliferative activities.
CHK-IN-1 can prevent DNA damage repair mechanism from arresting the cell cycle at the G2/M checkpoint[1].
[1]. Novel compounds and therapeutic use thereof for protein kinase inhibition. EP 2477496 A1