Refametinib R enantiomer 是一种 MEK 抑制剂，EC50为 2.0-15 nM，详细信息请参考专利文献WO2007014011A2 中的化合物 1022。
CAS：923032-38-6
分子式：C19H20F3IN2O5S
分子量：572.34
纯度：98%
存储：Store at -20°C

Background:

Refametinib R enantiomer is a MEK inhibitor extracted from patent WO2007014011A2, compound 1022, has an EC50 of 2.0-15 nM. MEK|2-15 nM (EC50)

Refametinib R enantiomer is the R enantiomer of Refametinib . Refametinib R enantiomer is an inhibitor of MEK and is useful in treatment of cancer and other hyperproliferative diseases[1].

[1]. Andreas Maderna, et al. N-(arylamino)-sulfonamide inhibitors of mek. WO 2007014011 A2.