Itacitinib adipate 是一个选择性 JAK1 抑制剂，已经在骨髓纤维化的 II 期试验中测试其疗效和安全性。
CAS：1334302-63-4
分子式：C32H33F4N9O5
分子量：699.66
纯度：98%
存储：Store at -20°C

Background:

Itacitinib adipate is an orally bioavailable and selective JAK1 inhibitor which has been tested for efficacy and safety in a phase II trial in myelofibrosis. JAK1

[1]. Griesshammer M, et al. The BCR-ABL1-negative myeloproliferative neoplasms: a review of JAK inhibitors in the therapeutic armamentarium. Expert Opin Pharmacother. 2017 Dec;18(18):1929-1938.