生物活性
Acarbose是一种肠道alpha-glucosidase抑制剂，用于治疗2型糖尿病以及某些国家的前驱糖尿病。
靶点信息
化学数据
| 目录号 | A10029 |
| M. Wt | 645.6 |
| Formula | C25H43NO18 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
| CAS No. | 56180-94-0 |
| Synonyms | Prandase, Precose, Glucobay, Bay-g 5421 |
| SMILES | C[C@@H]1[C@H]([C@@H]([C@H]([C@H](O1)O[C@@H]2[C@H](O[C@@H]([C@@H]([C@H]2O)O)O[C@@H]3[C@H](O[C@H]([C@@H]([C@H]3O)O)O)CO)CO)O)O)N[C@H]4C=C([C@H]([C@@H]([C@H]4O)O)O)CO |
溶解度
| In vitro | DMSO | 87 mg/mL (134.75 mM) |
| Water | 87 mg/mL (134.75 mM) |
| Ethanol | 7 mg/mL (10.84 mM) |
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
储备液配制
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
| 0.1 mM | 15.49 mL | 77.45 mL | 154.89 mL |
| 0.5 mM | 3.1 mL | 15.49 mL | 30.98 mL |
| 1 mM | 1.55 mL | 7.74 mL | 15.49 mL |
| 5 mM | 0.31 mL | 1.55 mL | 3.1 mL |
*The above data is based on the productmolecular weight 645.6 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
m.cnreagent.com