生物活性
Adefovir dipivoxil是口服的核苷酸类似物逆转录酶抑制剂（ntRTI）。
化学数据
| 目录号 | A10039 |
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 501.5 |
| Formula | C20H32N5O8P |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
| CAS No. | 142340-99-6 |
| Synonyms | Bis-POM PMEA, Preveon, Hepsera |
| SMILES | CC(C)(C)C(=O)OCOP(=O)(COCCN1C=NC2=C1N=CN=C2N)OCOC(=O)C(C)(C)C |
溶解度
| In vitro | DMSO | 85 mg/mL (169.5 mM) |
| Water | Insoluble |
| Ethanol | 85 mg/mL (169.5 mM) |
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
储备液配制
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
| 0.1 mM | 19.94 mL | 99.7 mL | 199.4 mL |
| 0.5 mM | 3.99 mL | 19.94 mL | 39.88 mL |
| 1 mM | 1.99 mL | 9.97 mL | 19.94 mL |
| 5 mM | 0.4 mL | 1.99 mL | 3.99 mL |
*The above data is based on the productmolecular weight 501.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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