生物活性
Andarine (GTX-007)是研究性的选择性雄激素受体调节剂（SARM）。
靶点信息
| Androgen Receptor | | | | |
| 4 nM(Ki) | | | | |
化学数据
| 目录号 | A10076 |
| 作用机制 | Agonist (激动剂) |
| M. Wt | 441.4 |
| Formula | C19H18F3N3O6 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
| CAS No. | 401900-40-1 |
| Synonyms | GTX-007, S-4, GTX007 |
| SMILES | CC(=O)NC1=CC=C(C=C1)OC[C@@](C)(C(=O)NC2=CC(=C(C=C2)[N+](=O)[O-])C(F)(F)F)O |
溶解度
| In vitro (25°C) | DMSO | 80 mg/mL (181.25 mM) |
| Water | Insoluble |
| Ethanol | 80 mg/mL (181.25 mM) |
| In vivo | 30% PEG400+0.5% Tween80+5% propylene glycol | 28 mg/mL |
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
储备液配制
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
| 0.1 mM | 22.66 mL | 113.28 mL | 226.55 mL |
| 0.5 mM | 4.53 mL | 22.66 mL | 45.31 mL |
| 1 mM | 2.27 mL | 11.33 mL | 22.66 mL |
| 5 mM | 0.45 mL | 2.27 mL | 4.53 mL |
*The above data is based on the productmolecular weight 441.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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