生物活性
Artemether (SM-224)已被证明具有显着的抗癌和抗肿瘤活性。 结果表明，蒿甲醚对大鼠脑神经胶质瘤的生长和血管生成具有强烈的抑制作用。
靶点信息
化学数据
| 目录号 | A10085 |
| M. Wt | 298.4 |
| Formula | C16H26O5 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
| CAS No. | 71963-77-4 |
| Synonyms | Dihydroqinghaosu methyl ether, SM-224 |
| SMILES | C[C@@H]1CC[C@H]2[C@H]([C@H](O[C@H]3[C@@]24[C@H]1CCC(O3)(OO4)C)OC)C |
溶解度
| In vitro | DMSO | 58 mg/mL (194.39 mM) |
| Water | Insoluble |
| Ethanol | 58 mg/mL (194.39 mM) |
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
储备液配制
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
| 0.1 mM | 33.51 mL | 167.56 mL | 335.12 mL |
| 0.5 mM | 6.7 mL | 33.51 mL | 67.02 mL |
| 1 mM | 3.35 mL | 16.76 mL | 33.51 mL |
| 5 mM | 0.67 mL | 3.35 mL | 6.7 mL |
*The above data is based on the productmolecular weight 298.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
m.cnreagent.com