生物活性
Azathioprine是一种免疫抑制药物，可抑制嘌呤合成和GTP结合蛋白Rac1活化，用于治疗器官移植和自身免疫性疾病。
靶点信息
化学数据
| 目录号 | A10107 |
| M. Wt | 277.3 |
| Formula | C9H7N7O2S |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
| CAS No. | 446-86-6 |
| Synonyms | Azasan, Imuran, Azamun, BW-57-322, NSC-39084 |
| SMILES | CN1C=NC(=C1SC2=NC=NC3=C2NC=N3)[N+](=O)[O-] |
溶解度
| In vitro | DMSO | 46 mg/mL (165.91 mM) |
| Water | Insoluble |
| Ethanol | Insoluble |
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
储备液配制
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
| 0.1 mM | 36.06 mL | 180.31 mL | 360.62 mL |
| 0.5 mM | 7.21 mL | 36.06 mL | 72.12 mL |
| 1 mM | 3.61 mL | 18.03 mL | 36.06 mL |
| 5 mM | 0.72 mL | 3.61 mL | 7.21 mL |
*The above data is based on the productmolecular weight 277.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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