E3 ligase Ligand-Linker Conjugates 34 包含用于 E3 泛素连接酶的 cIAP 配体和 linker。E3 ligase Ligand-Linker Conjugates 34 可通过 PROTAC 技术合成降解剂。
CAS：1225433-96-4
分子式：C37H47N3O8
分子量：661.78
纯度：98%
存储：Store at -20°C
Background:
E3 ligase Ligand-Linker Conjugates 34 incorporates a cIAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. E3 ligase Ligand-Linker Conjugates 34 can be used to design PROTAC degrader[1].
cIAP1
[1]. Itoh Y, et al. Design, synthesis and biological evaluation of nuclear receptor-degradation inducers. Bioorg Med Chem. 2011 Nov 15;19(22):6768-78.
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