4-Epidoxycycline is the 4-epimer hepatic metabolite of the antibiotic doxycycline .
CAS：6543-77-7
分子式：C22H24N2O8
分子量：444.4
纯度：98%
存储：Store at -20°C

Background:

4-Epidoxycycline is the 4-epimer hepatic metabolite of the antibiotic doxycycline . Unlike doxycycline, 4-epidoxycycline lacks antibiotic activity, therefore, it may not induce the intestinal inflammation in mice associated with doxycycline use. It is an alternative to doxycycline to inactivate the transactivator protein tTA or activate the reverse transactivator rtTA protein in Tet-Off- and Tet-On-based gene expression systems in vitro and in mice.