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(24S)-24,25-Dihydroxyvitamin D3
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
(24S)-24,25-Dihydroxyvitamin D3图片
CAS NO:55700-58-8
规格:98%
分子量:416.64
包装与价格:
包装价格(元)
10mg电议
50mg电议
1mg电议
5mg电议

产品介绍
Cholecalciferol是维生素D3的非活性形式。
CAS:55700-58-8
分子式:C27H44O3
分子量:416.64
纯度:98%
存储:Store at -20°C

Background:

(24S)-24,25-Dihydroxycholecalciferol is an inactive form of vitamin D3 which undergoes various levels of hydroxylation to form active vitamin D3 analogs. IC50 value:Target: Vitamin D3 analog1α-Hydroxyvitamin D3 (alfacalcidol) is a synthetic analog that is metabolized to 1,25-dihydroxycholecalciferol, the biologically active form of vitamin D3. Other analogues of cholecalciferol result from different hydroxylations. 24S,25-Dihydroxyvitamin D3 should not be confused with 24R,25-Dihydroxyvitamin D3.




[1]. Yamada S, Ino E, Takayama H et al. Differences in the side-chain metabolism of vitamin D3 between chickens and rats. Proc Natl Acad Sci U S A. 1985 Nov;82(22):7485-9. [2]. Kobayashi N, Higashi T, Saito K et al. Specificity of polyclonal antibodies raised against a novel 24,25-dihydroxyvitamin D3-bovine serum albumin conjugant linked through the C-11alpha or C-3 position. J Steroid Biochem Mol Biol. 1997 May;62(1):79-87. [3]. Larsson D, Nemere I, Sundell K. Putative basal lateral membrane receptors for 24,25-dihydroxyvitamin D(3) in carp and Atlantic cod enterocytes: characterization of binding and effects on intracellular calcium regulation. J Cell Biochem. 2001 Aug 1-9;83(2):171-86. [4]. Nemere I, Yazzie-Atkinson D, Johns DO, Larsson D. Biochemical characterization and purification of a binding protein for 24,25-dihydroxyvitamin D3 from chick intestine. J Endocrinol. 2002 Jan;172(1):211-9.