生物活性
Bimatoprost (Lumigan)是一种前列腺素类似物/前药，局部使用（作为滴眼剂）以控制青光眼的进展并用于治疗高眼压症
靶点信息
化学数据
| 目录号 | A10145 |
| M. Wt | 415.6 |
| Formula | C25H37NO4 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
| CAS No. | 155206-00-1 |
| Synonyms | Lumigan |
| SMILES | CCNC(=O)CCC/C=C\C[C@H]1[C@H](C[C@H]([C@@H]1/C=C/[C@H](CCC2=CC=CC=C2)O)O)O |
溶解度
| In vitro | DMSO | 31 mg/mL (74.59 mM) |
| Water | Insoluble |
| Ethanol | 71 mg/mL (170.84 mM) |
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
储备液配制
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
| 0.1 mM | 24.06 mL | 120.31 mL | 240.62 mL |
| 0.5 mM | 4.81 mL | 24.06 mL | 48.12 mL |
| 1 mM | 2.41 mL | 12.03 mL | 24.06 mL |
| 5 mM | 0.48 mL | 2.41 mL | 4.81 mL |
*The above data is based on the productmolecular weight 415.6 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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