生物活性
Carbidopa是一种芳香族-L-氨基酸脱羧酶抑制剂，这是一种在L-色氨酸生物合成5-羟色胺和L-DOPA生物合成多巴胺（DA）中重要的酶。
化学数据
| 目录号 | A10181 |
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 226.2 |
| Formula | C10H14N2O4 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
| CAS No. | 28860-95-9 |
| Synonyms | Lodosyn |
| SMILES | C[C@](CC1=CC(=C(C=C1)O)O)(C(=O)O)NN |
溶解度
| In vitro (25°C) | DMSO | 3 mg/mL (13.26 mM) |
| Water | Insoluble |
| Ethanol | Insoluble |
| In vivo | 4% DMSO+30% PEG 300+2% Tween 80+ddH2O | 1 mg/mL |
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
储备液配制
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
| 0.1 mM | 44.21 mL | 221.04 mL | 442.09 mL |
| 0.5 mM | 8.84 mL | 44.21 mL | 88.42 mL |
| 1 mM | 4.42 mL | 22.1 mL | 44.21 mL |
| 5 mM | 0.88 mL | 4.42 mL | 8.84 mL |
*The above data is based on the productmolecular weight 226.2 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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