生物活性
Chrysophanic acid (Chrysophanol)是通过抑制EGFR/mTOR通路来阻止结肠癌细胞的增殖。
靶点信息
化学数据
| 目录号 | A10210 |
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 254.2 |
| Formula | C15H10O4 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
| CAS No. | 481-74-3 |
| Synonyms | Chrysophanol, NSC 37132, NSC 646567 |
| SMILES | CC1=CC(=C2C(=C1)C(=O)C3=C(C2=O)C(=CC=C3)O)O |
溶解度
| In vitro | DMSO | Warmed: 5 mg/mL (19.66 mM) |
| Water | Insoluble |
| Ethanol | Insoluble |
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
储备液配制
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
| 0.1 mM | 39.34 mL | 196.7 mL | 393.39 mL |
| 0.5 mM | 7.87 mL | 39.34 mL | 78.68 mL |
| 1 mM | 3.93 mL | 19.67 mL | 39.34 mL |
| 5 mM | 0.79 mL | 3.93 mL | 7.87 mL |
*The above data is based on the productmolecular weight 254.2 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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