生物活性
Clarithromycin是一种大环内酯类抗生素。它通过干扰细菌的蛋白质合成来防止细菌生长。
靶点信息
化学数据
目录号 | A10225 |
作用机制 | Inhibitor (抑制剂) |
M. Wt | 748.0 |
Formula | C38H69NO13 |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for36 months. In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
CAS No. | 81103-11-9 |
Synonyms | A-56268, TE-03, Crixan, Claritt, Clarac, Biaxin, Klaricid, Klacid, Klaram, Klabax, Claripen, Clarem, Claridar, Fromilid, Clacid, Clacee, Vikrol, Infex, Clariwin, Resclar, Ranbaxy, Clarihexal |
SMILES | CC[C@@H]1[C@@]([C@@H]([C@H](C(=O)[C@@H](C[C@@]([C@@H]([C@H]([C@@H]([C@H](C(=O)O1)C)O[C@H]2C[C@@]([C@H]([C@@H](O2)C)O)(C)OC)C)O[C@H]3[C@@H]([C@H](C[C@H](O3)C)N(C)C)O)(C)OC)C)C)O)(C)O |
溶解度
In vitro | DMSO | Warmed: 25 mg/mL (33.42 mM) |
Water | Insoluble |
Ethanol | Insoluble |
*<1 mg/ml means slightly soluble or insoluble. *Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
储备液配制
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
0.1 mM | 13.37 mL | 66.84 mL | 133.69 mL |
0.5 mM | 2.67 mL | 13.37 mL | 26.74 mL |
1 mM | 1.34 mL | 6.68 mL | 13.37 mL |
5 mM | 0.27 mL | 1.34 mL | 2.67 mL |
*The above data is based on the productmolecular weight 748.0 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.