Guanosine5'-diphosphatedisodiumsalt是一种核苷二磷酸。Guanosine5'-diphosphate是一种潜在的铁动员剂,可阻断铁调素-铁转运蛋白相互作用并调节白细胞介素-6(IL-6)/stat-3途径。
CAS:7415-69-2
分子式:C10H13N5Na2O11P2
分子量:487.16
纯度:98%
存储:Store at -20°C
Background:
Guanosine 5’-diphosphate disodium salt is a nucleoside diphosphate. Guanosine 5’-diphosphate is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulating the interleukin-6 (IL-6)/stat-3 pathway[1].
[1]. Angmo S, et al. Identification of Guanosine 5’-diphosphate as Potential Iron Mobilizer: Preventing the Hepcidin-Ferroportin Interaction and Modulating the Interleukin-6/Stat-3 Pathway. Sci Rep. 2017 Jan 5;7:40097.