Bis-PEG4-acid是PEG的连接桥,应用于PROTAC中。
CAS:31127-85-2
分子式:C12H22O8
分子量:294.3
纯度:98%
存储:Store at -20°C
Background:
Bis-PEG4-acid is a PEG PROTAC linker.
PROTAC linker[1]
[1]. Maniaci C, et al. Homo-PROTACs: bivalent small-molecule dimerizers of the VHL E3 ubiquitin ligase to induce self-degradation. Nat Commun. 2017 Oct 10;8(1):830.