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Decitabine
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Decitabine图片
CAS NO:2353-33-5
包装与价格:
包装价格(元)
10mg电议
25mg电议
50mg电议
100mg电议
10mM * 1mL in DMSO电议

产品名称
Dacogen
产品介绍

生物活性

Decitabine是一种次甲基化剂,它通过抑制DNA甲基转移酶来使DNA次甲基化。

靶点信息

DNA methylation (HL-60, KG1a cells)

化学数据

目录号A10292
作用机制Inhibitor (抑制剂)
M. Wt228.2
FormulaC8H12N4O4
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.2353-33-5
SynonymsDacogen
SMILESC1[C@@H]([C@H](O[C@H]1N2C=NC(=NC2=O)N)CO)O

溶解度

In vitro (25°C)DMSO44 mg/mL (192.8 mM)
Water10 mg/mL (43.81 mM)
EthanolInsoluble
In vivowater9 mg/mL
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM43.82 mL219.11 mL438.21 mL
0.5 mM8.76 mL43.82 mL87.64 mL
1 mM4.38 mL21.91 mL43.82 mL
5 mM0.88 mL4.38 mL8.76 mL

*The above data is based on the productmolecular weight 228.2 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.