生物活性
Dihydroartemisinin是所有青蒿素化合物（青蒿素，青蒿琥酯，青蒿素等）的活性代谢产物，本身也可以用作药物。它是青蒿素的半合成衍生物，被广泛用作制备其他由青蒿素衍生的抗疟药物的中间体。
靶点信息
化学数据
| 目录号 | A10310 |
| M. Wt | 284.35 |
| Formula | C15H24O5 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
| CAS No. | 71939-50-9 |
| Synonyms | dihydroqinghaosu,artenimol, DHA |
| SMILES | [H][C@@]1(C([H])([H])C2([H])[H])[C@]3([C@@]([C@@]4([H])C([H])([H])[H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H])OO[C@@]2(C([H])([H])[H])O[C@@]3([H])O[C@@]4([H])O[H] |
溶解度
| In vitro | DMSO | Warmed: 52 mg/mL (182.87 mM) |
| Water | Insoluble |
| Ethanol | Warmed: 10 mg/mL (35.16 mM) |
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
储备液配制
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
| 0.1 mM | 35.17 mL | 175.84 mL | 351.68 mL |
| 0.5 mM | 7.03 mL | 35.17 mL | 70.34 mL |
| 1 mM | 3.52 mL | 17.58 mL | 35.17 mL |
| 5 mM | 0.7 mL | 3.52 mL | 7.03 mL |
*The above data is based on the productmolecular weight 284.35. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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