5-Hydroxyindole-3-aceticacid是5-羟色胺或甲氧基肾上腺素的主要代谢产物,被用作神经内分泌肿瘤的生物标志物。
CAS:54-16-0
分子式:C10H9NO3
分子量:191.18
纯度:98%
存储:Store at -20°C
Background:
5-Hydroxyindole-3-acetic acid is the main metabolite of serotonin or metanephrines, which can be used as a biomarker of neuroendocrine tumors.
5-Hydroxyindole-3-acetic acid (5HIAA) is a metabolite issued from serotonin metabolism, and the latter is synthetized from the essential amino acid tryptophan. Serotonin is mainly metabolised by monoamine oxidase in the liver and the lungs[1].
[1]. Corcuff JB, et al. Urinary sampling for 5HIAA and metanephrines determination: revisiting the recommendations. Endocr Connect. 2017 Aug;6(6):R87-R98.