生物活性
Marbofloxacin是有效的第三代氟喹诺酮类抗生素，通过抑制细菌DNA复制起作用。
靶点信息
| Topoisomerase II | Topoisomerase IV | | | |
| | | | |
化学数据
| 目录号 | A10557 |
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 362.4 |
| Formula | C17H19FN4O4 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
| CAS No. | 115550-35-1 |
| Synonyms | Marbocyl,Zeniquin |
| SMILES | CN1CCN(CC1)C2=C(C=C3C4=C2OCN(N4C=C(C3=O)C(=O)O)C)F |
溶解度
| In vitro (25°C) | DMSO | Warmed: 3 mg/mL (8.27 mM) |
| Water | Insoluble |
| Ethanol | Insoluble |
| In vivo | 1% DMSO+30% polyethylene glycol+1% Tween 80, pH 4 | 13 mg/mL |
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
储备液配制
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
| 0.1 mM | 27.59 mL | 137.97 mL | 275.94 mL |
| 0.5 mM | 5.52 mL | 27.59 mL | 55.19 mL |
| 1 mM | 2.76 mL | 13.8 mL | 27.59 mL |
| 5 mM | 0.55 mL | 2.76 mL | 5.52 mL |
*The above data is based on the productmolecular weight 362.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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