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BO3482
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
BO3482图片
CAS NO:198013-53-5
规格:98%
分子量:383.44
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议

产品介绍
BO-3482有抗菌活性,可用于抑制耐甲氧西林的金黄色葡萄球菌,其MIC90值为6.25μg/mL。
CAS:198013-53-5
分子式:C14H20N2NaO5S2
分子量:383.44
纯度:98%
存储:Store at -20°C

Background:

BO3482 has Antimicrobial activity and can inhibit the growth of methicillin-resistant Staphylococci (MRS) with an MIC90 of 6.25 mg/mL.



In the thigh infection model with a homogeneous MRSA strain, the bacterial counts in tissues treated with BO3482-cilastatin are significantly reduced in a dose-dependent manner compare with the counts in those treat with vancomycin and imipenem-cilastatin[1].


[1]. Adachi Y, et al. In vitro evaluation of BO-3482, a novel dithiocarbamate carbapenem with activity against methicillin-resistant staphylococci. Antimicrob Agents Chemother. 1997 Oct;41(10):2282-5. [2]. Nagano R, et al. Therapeutic efficacy of BO-3482, a novel dithiocarbamate carbapenem, in mice infected with methicillin-resistant Staphylococcus aureus. Antimicrob Agents Chemother. 1997 Oct;41(10):2278-81.