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Paclitaxel(Taxol)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Paclitaxel(Taxol)图片
CAS NO:33069-62-4
包装与价格:
包装价格(元)
10mg电议
50mg电议
100mg电议
200mg电议
10mM * 1mL in DMSO电议

产品名称
Taxol
产品介绍

生物活性

Paclitaxel (Taxol)是一种有丝分裂抑制剂,可稳定微管,从而干扰细胞分裂过程中微管的正常分解,在人内皮细胞中IC50为0.1pM。

靶点信息

Microtubule (human endothelial cells)
0.1 pM

化学数据

目录号A10689
作用机制Inhibitor (抑制剂)
M. Wt853.9
FormulaC47H51NO14
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.33069-62-4
SynonymsTaxol
SMILESCC1=C2[C@H](C(=O)[C@@]3([C@H](C[C@@H]4[C@]([C@H]3[C@@H]([C@@](C2(C)C)(C[C@@H]1OC(=O)[C@@H]([C@H](C5=CC=CC=C5)NC(=O)C6=CC=CC=C6)O)O)OC(=O)C7=CC=CC=C7)(CO4)OC(=O)C)O)C)OC(=O)C

溶解度

In vitro (25°C)DMSO152 mg/mL (178 mM)
WaterInsoluble
Ethanol16 mg/mL (18.73 mM)
In vivo5% DMSO+40% PEG 300+5% Tween 80+ddH2O5 mg/mL
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM11.71 mL58.55 mL117.11 mL
0.5 mM2.34 mL11.71 mL23.42 mL
1 mM1.17 mL5.86 mL11.71 mL
5 mM0.23 mL1.17 mL2.34 mL

*The above data is based on the productmolecular weight 853.9 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.