您好,欢迎来到试剂信息网! [登录] [免费注册]
试剂信息网
位置:首页 > 产品库 > PCI-24781(Abexinostat)
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
PCI-24781(Abexinostat)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
PCI-24781(Abexinostat)图片
CAS NO:783355-60-2
包装与价格:
包装价格(元)
5mg电议
10mg电议
50mg电议
100mg电议
10mM * 1mL in DMSO电议

产品名称
PCI24781, CRA-024781
产品介绍

生物活性

PCI-24781 (Abexinostat)是一种广谱苯基异羟肟酸HDAC抑制剂。

Targets

TargetValue
HDAC1ki: 7nM
HDAC3/SMRTki: 8.2nM
HDAC6ki: 17nM
HDAC2ki: 19nM
HDAC10IC50: 24nM
HDAC8IC50: 280nM

化学数据

目录号A10700
作用机制Inhibitor (抑制剂)
M. Wt397.4
FormulaC21H23N3O5
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.783355-60-2
SynonymsPCI24781, CRA-024781
SMILESCN(C)CC1=C(OC2=CC=CC=C21)C(=O)NCCOC3=CC=C(C=C3)C(=O)NO

溶解度

In vitroDMSO72 mg/mL (181.16 mM)
WaterInsoluble
EthanolInsoluble
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM25.16 mL125.82 mL251.64 mL
0.5 mM5.03 mL25.16 mL50.33 mL
1 mM2.52 mL12.58 mL25.16 mL
5 mM0.5 mL2.52 mL5.03 mL

*The above data is based on the productmolecular weight 397.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.