PROTACBET-bindingmoiety1是合成高亲和力BET抑制剂的一个关键中间体。
CAS：2093387-77-8
分子式：C25H25N7O4
分子量：487.51
纯度：98%
存储：Store at -20°C

Background:

PROTAC BET-binding moiety 1 is a key intermediate for the synthesis of high-affinity BET inhibitors[1].

[1]. Zhou B, et al. Discovery of a Small-Molecule Degrader of Bromodomain and Extra-Terminal (BET) Proteins with Picomolar Cellular Potencies and Capable of Achieving Tumor Regression. J Med Chem. 2018 Jan 25;61(2):462-481.