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STF-62247
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
STF-62247图片
CAS NO:315702-99-9
包装与价格:
包装价格(元)
10mg电议
25mg电议
50mg电议
100mg电议
10mM * 1mL in DMSO电议

产品名称
STF62247
产品介绍

生物活性

STF-62247是一种小分子激动剂,可诱导已经失去von Hippel-Lindau(VHL)肿瘤抑制活性(IC50 = 625 nM)的肾细胞癌(RCC)细胞致死,并自噬。

靶点信息

化学数据

目录号A10866
作用机制Inducer (诱导剂)
M. Wt267.4
FormulaC15H13N3S
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.315702-99-9
SynonymsSTF62247
SMILESCC1=CC(=CC=C1)NC2=NC(=CS2)C3=CC=NC=C3

溶解度

In vitro (25°C)DMSO47 mg/mL (175.8 mM)
WaterInsoluble
Ethanol3 mg/mL (11.22 mM)
In vivo1% DMSO+30% polyethylene glycol+1% Tween 806 mg/mL
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM37.4 mL186.99 mL373.97 mL
0.5 mM7.48 mL37.4 mL74.79 mL
1 mM3.74 mL18.7 mL37.4 mL
5 mM0.75 mL3.74 mL7.48 mL

*The above data is based on the productmolecular weight 267.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.