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PtdIns-(3,4,5)-P3(1,2-dihexanoyl)(ammonium salt)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
PtdIns-(3,4,5)-P3(1,2-dihexanoyl)(ammonium salt)图片
CAS NO:799268-62-5
规格:98%
分子量:838.6
包装与价格:
包装价格(元)
100ug电议
500ug电议
1mg电议

产品介绍
The phosphatidylinositol (PtdIns) phosphates represent a small percentage of total membrane phospholipids.
CAS:799268-62-5
分子式:C21H54N4O22P4.4NH4
分子量:838.6
纯度:98%
存储:Store at -20°C

Background:

The phosphatidylinositol (PtdIns) phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals. PtdIns-(3,4,5)-P3, also known as PIP3, is resistant to cleavage by PI-specific phospholipase C (PLC). Thus, it is likely to function in signal transduction as a modulator in its own right, rather than as a source of inositol tetraphosphates. PIP3 can serve as an anchor for the binding of signal transduction proteins bearing pleckstrin homology (PH) domains. Protein binding to PIP3 is important for cytoskeletal rearrangement and membrane trafficking. PtdIns-(3,4,5)-P3 (1,2-dihexanoyl) is a synthetic analog of natural PIP3 with C6:0 fatty acids at the sn-1 and sn-2 positions. The compound features the same inositol and diacylglycerol (DAG) stereochemistry as that of the natural compound. The short fatty acid chains of this analog give it different physical properties from naturally-occurring PIP3, including higher solubility in aqueous media.