您好,欢迎来到试剂信息网! [登录] [免费注册]
试剂信息网
位置:首页 > 产品库 > Plerixafor 8HCl(DB06809)
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
Plerixafor 8HCl(DB06809)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Plerixafor 8HCl(DB06809)图片
CAS NO:155148-31-5
包装与价格:
包装价格(元)
10mg电议
25mg电议
50mg电议
100mg电议

产品名称
DB06809, AMD3100, Mozobil
产品介绍

生物活性

Plerixafor 8HCl (DB06809)是CXCR4趋化因子受体拮抗剂,作用于CXCR4和CXCL12介导调节的趋化性, IC50分别为44 nM和5.7 nM。

靶点信息

CXCL12-mediated chemotaxis (Cell-free assay)CXCR4 (Cell-free assay)
5.7 nM44 nM

化学数据

目录号A10913
作用机制Antagonist (拮抗剂)
M. Wt794.5
FormulaC28H54N8.8HCl
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.155148-31-5
SynonymsDB06809, AMD3100, Mozobil
SMILESC1CNCCNCCCN(CCNC1)CC2=CC=C(C=C2)CN3CCCNCCNCCCNCC3.Cl.Cl.Cl.Cl.Cl.Cl.Cl.Cl

溶解度

In vitro (25°C)DMSOInsoluble
Water91 mg/mL (114.54 mM)
EthanolInsoluble
In vivoSaline28 mg/mL
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM12.59 mL62.93 mL125.87 mL
0.5 mM2.52 mL12.59 mL25.17 mL
1 mM1.26 mL6.29 mL12.59 mL
5 mM0.25 mL1.26 mL2.52 mL

*The above data is based on the productmolecular weight 794.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.