生物活性
Tetrahydropapaverine HCl是TIQs的一种，是Salsolinol和Tetrahydropapaveroline的类似物，对多巴胺神经元具有神经毒性作用。
靶点信息
| Tryptophan hydroxylase | | | | |
| 5.7 μM | | | | |
化学数据
| 目录号 | A10920 |
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 379.9 |
| Formula | C20H25NO4.HCl |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
| CAS No. | CAS: 6429-04-5 |
| SMILES | COC1=C(C=C(C=C1)CC2C3=CC(=C(C=C3CCN2)OC)OC)OC.Cl |
溶解度
| In vitro | DMSO | 7 mg/mL (18.42 mM) |
| Water | 74 mg/mL (194.8 mM) |
| Ethanol | Insoluble |
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
储备液配制
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
| 0.1 mM | 26.32 mL | 131.61 mL | 263.23 mL |
| 0.5 mM | 5.26 mL | 26.32 mL | 52.65 mL |
| 1 mM | 2.63 mL | 13.16 mL | 26.32 mL |
| 5 mM | 0.53 mL | 2.63 mL | 5.26 mL |
*The above data is based on the productmolecular weight 379.9 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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