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Thiazovivin
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Thiazovivin图片
CAS NO:1226056-71-8
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议
10mM * 1mL in DMSO电议

产品介绍

生物活性

Thiazovivin是一种Rho相关激酶(ROCK)的选择性抑制剂。

靶点信息

ROCK (Cell-free assay)
~0.5 μM

化学数据

目录号A10928
作用机制Inhibitor (抑制剂)
M. Wt311.4
FormulaC15H13N5OS
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.1226056-71-8
SMILESC1=CC=C(C=C1)CNC(=O)C2=CSC(=N2)NC3=NC=NC=C3

溶解度

In vitro (25°C)DMSO15 mg/mL (48.17 mM)
WaterInsoluble
EthanolInsoluble
In vivo30% PEG400+0.5% Tween80+5% propylene glycol28 mg/mL
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM32.11 mL160.57 mL321.13 mL
0.5 mM6.42 mL32.11 mL64.23 mL
1 mM3.21 mL16.06 mL32.11 mL
5 mM0.64 mL3.21 mL6.42 mL

*The above data is based on the productmolecular weight 311.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.