Lerociclib(G1T38)dihydrochloride是一种有效的选择性CDK4/CDK6抑制剂，抑制CDK4/CyclinD1和CDK6/CyclinD3，IC50值分别为1nM和2nM。
CAS：2097938-59-3
分子式：C26H36Cl2N8O
分子量：547.52
纯度：98%
存储：Store at -20°C

Background:

Lerociclib (G1 T38) dihydrochloride is a potent and selective inhibitor of CDK4/CDK6, with IC50s of 1 nM and 2 nM for CDK4/CyclinD1 and CDK6/CyclinD3, respectively.

Within the CDK family, Lerocyclib is least selective against CDK9/cyclin T,