生物活性
Yohimbine hydrochloride (Antagonil) 是一种α2-肾上腺素受体拮抗剂（人类α2A，α2B和α2C受体的pKi值分别为8.52、8.00和9.17）。
化学数据
| 目录号 | A11003 |
| M. Wt | 390.9 |
| Formula | C21H26N2O3.HCl |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
| CAS No. | 65-19-0 |
| Synonyms | Antagonil, Yohimbe, Aphrodine hydrochloride, Yohimbine monohydrochloride |
| SMILES | COC(=O)[C@H]1[C@H](CC[C@@H]2[C@@H]1C[C@H]3C4=C(CCN3C2)C5=CC=CC=C5N4)O.Cl |
溶解度
| In vitro | DMSO | Warmed: 11 mg/mL (28.13 mM) |
| Water | Insoluble |
| Ethanol | Insoluble |
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
储备液配制
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
| 0.1 mM | 25.58 mL | 127.91 mL | 255.82 mL |
| 0.5 mM | 5.12 mL | 25.58 mL | 51.16 mL |
| 1 mM | 2.56 mL | 12.79 mL | 25.58 mL |
| 5 mM | 0.51 mL | 2.56 mL | 5.12 mL |
*The above data is based on the productmolecular weight 390.9 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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