生物活性
Nitrisinone是一种竞争性抑制剂,可逆地抑制4-羟基苯基丙酮酸氧化酶(双加氧酶)。
化学数据
目录号 | A11093 |
作用机制 | Inhibitor (抑制剂) |
M. Wt | 329.2 |
Formula | C14H10F3NO5 |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for36 months. In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
CAS No. | 104206-65-7 |
Synonyms | SC 0735, NTBC |
SMILES | C1CC(=O)C(C(=O)C1)C(=O)C2=C(C=C(C=C2)C(F)(F)F)[N+](=O)[O-] |
溶解度
In vitro | DMSO | 62 mg/mL (188.32 mM) |
Water | Insoluble |
Ethanol | Insoluble |
*<1 mg/ml means slightly soluble or insoluble. *Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
储备液配制
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
0.1 mM | 30.38 mL | 151.88 mL | 303.77 mL |
0.5 mM | 6.08 mL | 30.38 mL | 60.75 mL |
1 mM | 3.04 mL | 15.19 mL | 30.38 mL |
5 mM | 0.61 mL | 3.04 mL | 6.08 mL |
*The above data is based on the productmolecular weight 329.2 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.