生物活性
Folinic acid calcium salt (Leucovorin)是B复合维生素叶酸的活性形式，被用作抗癌药（例如甲氨蝶呤）的解毒剂，以减少残留药物的毒性。
化学数据
| 目录号 | A11110 |
| M. Wt | 511.51 |
| Formula | C20H21N7O7.Ca |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
| CAS No. | 1492-18-8 |
| SMILES | C1C(N(C2=C(N1)NC(=NC2=O)N)C=O)CNC3=CC=C(C=C3)C(=O)N[C@@H](CCC(=O)[O-])C(=O)[O-].[Ca+2] |
溶解度
| In vitro | DMSO | Insoluble |
| Water | 90 mg/mL (175.95 mM) |
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
储备液配制
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
| 0.1 mM | 19.55 mL | 97.75 mL | 195.5 mL |
| 0.5 mM | 3.91 mL | 19.55 mL | 39.1 mL |
| 1 mM | 1.95 mL | 9.77 mL | 19.55 mL |
| 5 mM | 0.39 mL | 1.95 mL | 3.91 mL |
*The above data is based on the productmolecular weight 511.51. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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