生物活性
3-Methyladenine是III类磷脂酰肌醇3-激酶（PI 3-激酶）的抑制剂。
靶点信息
| Vps34 (HeLa cells) | PI3Kγ (HeLa cells) | | | |
| 25 μM | 60 μM | | | |
化学数据
| 目录号 | A11151 |
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 149.2 |
| Formula | C6H7N5 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
| CAS No. | 5142-23-4 |
| Synonyms | 3-MA |
| SMILES | CN1C=NC(=C2C1=NC=N2)N |
溶解度
| In vitro | DMSO | Warmed: 3 mg/mL (20.11 mM) |
| Water | Warmed: 10 mg/mL (67.04 mM) |
| Ethanol | 4 mg/mL (26.81 mM) |
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
储备液配制
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
| 0.1 mM | 67.02 mL | 335.12 mL | 670.24 mL |
| 0.5 mM | 13.4 mL | 67.02 mL | 134.05 mL |
| 1 mM | 6.7 mL | 33.51 mL | 67.02 mL |
| 5 mM | 1.34 mL | 6.7 mL | 13.4 mL |
*The above data is based on the productmolecular weight 149.2 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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