Pridopidine是一种多巴胺(DA)稳定剂,可用作一种低亲和力的多巴胺D2受体(D2R)拮抗剂。Pridopidine高亲和力作用于sigma1受体(S1R),Ki值为70到80nM,比其对D2R的亲和力高约100倍。
CAS:346688-38-8
分子式:C15H23NO2S
分子量:281.41
纯度:98%
存储:Store at -20°C
Background:
Pridopidine, a dopamine (DA) stabilizer, acts as a low affinity dopamine D2 receptor (D2R) antagonist. Pridopidine exerts high affinity towards sigma 1 receptor (S1R) with Ki between 70 and 80 nM, which is