生物活性
T-705 (Favipiravir)是一种有效的选择性RNA-dependent RNA polymerase抑制剂，在体外和体内均表现出有效的抗流感病毒活性。
靶点信息
| RNA-dependent RNA polymerase | | | | |
| | | | |
化学数据
| 目录号 | A11590 |
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 157.1 |
| Formula | C5H4FN3O2 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
| CAS No. | 259793-96-9 |
| Synonyms | T705, T 705 |
| SMILES | C1=C(N=C(C(=O)N1)C(=O)N)F |
溶解度
| In vitro | DMSO | 29 mg/mL (184.59 mM) |
| Water | Warmed: 5 mg/mL (31.82 mM) |
| Ethanol | Warmed: 21 mg/mL (133.67 mM) |
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
储备液配制
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
| 0.1 mM | 63.65 mL | 318.27 mL | 636.54 mL |
| 0.5 mM | 12.73 mL | 63.65 mL | 127.31 mL |
| 1 mM | 6.37 mL | 31.83 mL | 63.65 mL |
| 5 mM | 1.27 mL | 6.37 mL | 12.73 mL |
*The above data is based on the productmolecular weight 157.1. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
m.cnreagent.com