Prostaglandin H2 (PGH2) was first isolated from incubations of arachidonic acid with ovine seminal vesicle microsomes, and was described as a potent vasoconstrictor.
CAS：42935-17-1
分子式：C20H32O5
分子量：352.5
纯度：98%
存储：Store at -20°C

Background:

Prostaglandin H2 (PGH2) was first isolated from incubations of arachidonic acid with ovine seminal vesicle microsomes, and was described as a potent vasoconstrictor.[1]? PGH2 is the precursor for all 2-series PGs and thromboxanes (TXs), [2]? and is a TP receptor agonist which irreversibly aggregates human platelets at 50-100 ng/ml.

Reference：
[1]. Hamberg, M., Svensson, J., Wakabayashi, T., et al. Isolation and structure of two prostaglandin endoperoxides that cause platelet aggregation. Proceedings of the National Academy of Sciences of the United States of America 71, 345-349 (1974).
[2]. Samuelsson, B., Goldyne, M., Granstr?m, E., et al. Prostaglandins and thromboxanes. Annu. Rev. Biochem. 47, 997-1029 (1978).