Fluorescent dye, selective astrocyte marker
CAS：60311-02-6
分子式：C31H30N2O7S2
分子量：606.71
纯度：98%
存储：Store at -20°C

Background:

Sulforhodamine 101 is a red fluorescent dye.

Sulforhodamine 101 does not label astrocytes in brainstem slices as strong and specific as in the hippocampus or cortex. To minimize excitatory side effects, the concentration of Sulforhodamine 101 has to be kept as low as possible or the labeling procedure can be performed after the actual experiment[1].

In vivo, epileptic activity can be induced by intra-hippocampal injection of small volumes of 10 μM Sulforhodamine 101 or topical application of 100 μM[1].

参考文献:
[1]. Hülsmann S, et al. Limitations of Sulforhodamine 101 for Brain Imaging. Front Cell Neurosci. 2017 Feb 28;11:44.