生物活性
Brinzolamide是一种碳酸酐酶抑制剂，IC50为3.19 nM。
靶点信息
化学数据
| 目录号 | A11765 |
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 383.5 |
| Formula | C12H21N3O5S3 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
| CAS No. | 138890-62-7 |
| Synonyms | Azopt |
| SMILES | CCN[C@H]1CN(S(=O)(=O)C2=C1C=C(S2)S(=O)(=O)N)CCCOC |
溶解度
| In vitro | DMSO | 75 mg/mL (195.56 mM) |
| Water | Insoluble |
| Ethanol | Insoluble |
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
储备液配制
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
| 0.1 mM | 26.08 mL | 130.38 mL | 260.76 mL |
| 0.5 mM | 5.22 mL | 26.08 mL | 52.15 mL |
| 1 mM | 2.61 mL | 13.04 mL | 26.08 mL |
| 5 mM | 0.52 mL | 2.61 mL | 5.22 mL |
*The above data is based on the productmolecular weight 383.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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