生物活性
BAY 80-6946 (Copanlisib)是具有潜在抗肿瘤活性的磷酸肌醇3激酶（PI3K）抑制剂。
化学数据
| 目录号 | A11766 |
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 480.2 |
| Formula | C23H28N8O4 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
| CAS No. | 1032568-63-0 |
| Synonyms | BAY80-6946, BAY806946 |
| SMILES | COC1=C(C=CC2=C1N=C(N3C2=NCC3)NC(=O)C4=CN=C(N=C4)N)OCCCN5CCOCC5 |
溶解度
| In vitro | DMSO | Insoluble |
| Water | Insoluble |
| Ethanol | Insoluble |
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
储备液配制
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
| 0.1 mM | 20.82 mL | 104.12 mL | 208.25 mL |
| 0.5 mM | 4.16 mL | 20.82 mL | 41.65 mL |
| 1 mM | 2.08 mL | 10.41 mL | 20.82 mL |
| 5 mM | 0.42 mL | 2.08 mL | 4.16 mL |
*The above data is based on the productmolecular weight 480.2 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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