GW 405833 is a partial agonist of the cannabinoid CB2 receptor (EC50 = 0.65 nM).
CAS:180002-83-9
分子式:C23H24Cl2N2O3
分子量:447.4
纯度:98%
存储:Store at -20°C
Background:
GW 405833 is a partial agonist of the cannabinoid CB2 receptor (EC50 = 0.65 nM). It is selective for CB2, binding with a Ki value of 14 nM compared to that of CB1 with a Ki value of 2.04 uM. GW 405833 demonstrates anti-inflammatory and antihyperalgesic properties in animal models of inflammation and pain.