Celecoxib carboxylic acid acyl-β-D-glucuronide is a phase II metabolite of celecoxib.
CAS：264236-79-5
分子式：C23H20F3N3O10S
分子量：587.5
纯度：98%
存储：Store at -20°C

Background:

Celecoxib carboxylic acid acyl-β-D-glucuronide is a phase II metabolite of celecoxib . Celecoxib is an anti-inflammatory compound from the diaryl heterocycle class that selectively inhibits cyclooxygenase-2 (COX-2; IC50s = 22.9 and 0.05 μM for COX-1 and COX-2, respectively). Celecoxib carboxylic acid acyl-β-D-glucuronide is a minor metabolite, accounting for 2% of the administered dose in human urine and rat bile.