生物活性
A 967079是选择性TRPA1通道阻滞剂(人和大鼠TRPA1受体的IC50值分别为67和289 nM)。
化学数据
| 目录号 | A12353 |
| 作用机制 | Blocker (阻断剂) |
| M. Wt | 207.24 |
| Formula | C12H14FNO |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
| CAS No. | 1170613-55-4 |
| Synonyms | A-967079, A967079 |
| SMILES | CC/C(=N/O)/C(=C/C1=CC=C(C=C1)F)/C |
储备液配制
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
| 0.1 mM | 48.25 mL | 241.27 mL | 482.53 mL |
| 0.5 mM | 9.65 mL | 48.25 mL | 96.51 mL |
| 1 mM | 4.83 mL | 24.13 mL | 48.25 mL |
| 5 mM | 0.97 mL | 4.83 mL | 9.65 mL |
*The above data is based on the productmolecular weight 207.24. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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