您好,欢迎来到试剂信息网! [登录] [免费注册]
试剂信息网
位置:首页 > 产品库 > Pitavastatin lactone
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
Pitavastatin lactone
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Pitavastatin lactone图片
CAS NO:141750-63-2
规格:98%
分子量:403.5
包装与价格:
包装价格(元)
500ug电议
1mg电议
5mg电议

产品介绍
Pitavastatin lactone is a major phase 2 metabolite of pitavastatin, an inhibitor of HMG-CoA reductase, that is found in plasma of rats and humans following oral administration.
CAS:141750-63-2
分子式:C25H22FNO3
分子量:403.5
纯度:98%
存储:Store at -20°C

Background:

Pitavastatin lactone is a major phase 2 metabolite of pitavastatin , an inhibitor of HMG-CoA reductase, that is found in plasma of rats and humans following oral administration., Pitavastatin lactone is formed when pitavastatin undergoes glucuronidation by the UDP-glucuronysyl transferases UGT1A1, UGT1A3, or UGT2B7 to form pitavastatin glucuronide, which then undergoes non-enzymatic conversion to pitavastatin lactone. It can be converted back to pitavastatin via hydrolysis.